Type Journal Article
Author Jordan Krechmer
Author Felipe Lopez-Hilfiker
Author Abigail Koss
Author Manuel Hutterli
Author Carsten Stoermer
Author Benjamin Deming
Author Joel Kimmel
Author Carsten Warneke
Author Rupert Holzinger
Author John T. Jayne
Author Douglas R. Worsnop
Author Katrin Fuhrer
Author Marc Gonin
Author Joost A. de Gouw
URL https://doi.org/10.1021/acs.analchem.8b02641
Publication Analytical Chemistry
ISSN 0003-2700
Date September 17, 2018
Journal Abbr Anal. Chem.
DOI 10.1021/acs.analchem.8b02641
Accessed 2018-09-27 21:16:05
Library Catalog ACS Publications
Abstract We evaluate the performance of a new chemical ionization source called Vocus, consisting of a discharge reagent-ion source and focusing ion-molecule reactor (FIMR) for use in proton-transfer-reaction time-of-flight mass spectrometry (PTR-TOF) measurements of volatile organic compounds (VOCs) in air. The reagent ion source uses a low-pressure discharge. The FIMR consists of a glass tube with a resistive coating, mounted inside a radio-frequency (RF) quadrupole. The axial electric field is used to enhance ion collision energies and limit cluster ion formation. The RF field focuses ions to the central axis of the reactor and improves the detection efficiency of product ions. Ion trajectory calculations demonstrate the mass-dependent focusing of ions and enhancement of the ion collision energy by the RF field, in particular for the lighter ions. Product ion signals are increased by a factor of 10 when the RF field is applied (5,000-18,000 cps ppbv-1), improving measurement precision and detection limits while operating at very similar reaction conditions as traditional PTR instruments. Due to the high water mixing ratio in the FIMR, we observe no dependence of the sensitivity on ambient sample humidity. In this work, the Vocus is interfaced to a TOF mass analyzer with a mass resolving power up to 12,000, which allows clear separation of isobaric ions, observed at nearly every nominal mass when measuring ambient air. Measurement response times are determined for a range of ketones with saturation vapor concentrations down to 5×104 µg m-3 and compare favorably with previously published results for a PTR-MS instrument.